A Chromosome RNAissance
نویسندگان
چکیده
In RNA-mediated interference (RNAi), double-stranded RNAs (dsRNAs) target complementary mRNAs for degradation. New work demonstrates that essential chromosomal functions are mediated through RNAi protein components and short RNAs, which alter chromosome function at specific DNA loci via histone modification.
منابع مشابه
Ligand mimicry? Plant-parasitic nematode polypeptide with similarity to CLAVATA3.
DNA methylation and histone H3 lysine 9 methylation. Curr. Biol. 12, 1360 3 Richards, E.J. and Elgin, S.C. (2002) Epigenetic codes for heterochromatin formation and silencing: rounding up the usual suspects. Cell 108, 489–500 4 Bartee, L. et al. (2001) Arabidopsis cmt3 chromomethylase mutations block non-CG methylation and silencing of an endogenous gene. Genes Dev. 15, 1753–1758 5 Lindroth, A....
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ورودعنوان ژورنال:
- Cell
دوره 111 شماره
صفحات -
تاریخ انتشار 2002